THE CAPABILITIES ARE UNIQUELY ENABLED BY THE PROFLUIDICS 285D AND ARE FULLY COMPATIBLE ONLY WITH THIS SYSTEM.

Features at a Glance

>90% Cell Viability

Validated across 5 distinct cell lines both suspension and adherent types.

Broad-Spectrum Biocompatibility

Designed to interact with biological systems without causing toxicity or other harmful effects.

Optical Transparency

Delivers excellent clarity with minimal haze and no yellowing for effective on-chip evaluations.

Low Autofluorescence

Inert under fluorescent light to ensure accurate imaging of cells labeled with fluorescent dyes.

Proved by Researchers

>90% Cell Viability

Rigorous viability testing was performed on 5 cell lines. Suspension cells were injected into an assay 3D printed with the Cyto-Clear, stained with viability reagents, and analyzed on-chip using live/dead staining.

Adherent cells
 were subcultured onto 3D printed disks with the Cyto-Clear, stained with viability reagents, and then analyzed using an XTT assay and live/dead staining.

⬇ See the Difference under the microscope⬇

Before imageAfter image
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On-Hand Experience

Broad-Spectrum

Biocompatibility​

Cyto-Clear is a biocompatible material, enabling microfluidic devices to integrate with biological systems without causing adverse reactions. It’s a great solution for a wide range of research applications, from drug testing and delivery to point-of-care diagnostics.

Inert Under Fluorescent Light

Cyto-Clear offers low autofluorescence for accurate imaging of cells labeled with fluorescent dyes and markers. It is also UV-inert – an important feature that prevents material degradation or discoloration during specific microscopy techniques. The Cyto-Clear Photopolymer Resin remains stable under UV exposure, ensuring consistent performance and reliable results.

Inert Under Fluorescent Light

Cyto-Clear offers low autofluorescence for accurate imaging of cells labeled with fluorescent dyes and markers. It is also UV-inert – an important feature that prevents material degradation or discoloration during specific microscopy techniques. The Cyto-Clear Photopolymer Resin remains stable under UV exposure, ensuring consistent performance and reliable results.

Optically Clear

Cyto-Clear is specially formulated for high optical transparency, with visibly clear closed channels without the need for sanding, polishing, or additional processing. Its clarity – free from yellow tints – makes it ideal for on-chip evaluation of fluid flows and interactions, whether by eye or under a microscope.

Real Video. Not Rendered.

Alive to See

With Cyto-Clear, benchside cell research can now be done in just one day. This breakthrough 3D material is specifically formulated for cell-viable experiments, enabling researchers to test various cell types using 3D-printed devices. Up to 90% of the cells can survive after 48 hours, providing greater flexibility and convenience for drug testing and experimental workflows.

3 Easy Steps to 3D Print Devices

How do you build devices with the Cyto-Clear? It is simpler than we think to apply 3D Printing in microfluidics research. It is a straightforward and efficient process that can be completed in 3 steps: 

 

POUR, PRINT, CLEAN

 

This streamlined workflow enables the fabrication of high-resolution, transparent microfluidic devices at bench side within a single working day.

Applications

Every microfluidic device is simply a network of channels or features – from straight, serpentine, and spiral channels, to droplet generators, mixers, and viewing chambers. The Cyto-Clear Photopolymer Resin captures these intricate structures – and more – with precision and accuracy

Are These Challenges Holding Back Your Research?

No CAD Experience? We have a solution.

We collaborated with FLUI’DEVICE, a simple drag-and-drop platform that lets you design devices easily – No CAD skills are required.

Hear how Cyto-Clear started and proved itself.

In the Big Ideas at µScale podcast, we chat with the University of Waterloo researchers who played a big role in the R&D of Cyto-Clear.

Interested in Cyto-Clear?

The capabilities of Cyto-Clear are uniquely enabled by the ProFluidics 285d and are fully compatible only with this system.

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